8th October — 12:00 UTC (check local time)
Head of the Neurotrophins in Alzheimer's Lab. Professor of Neuroscience, School of Biomedical Science and Queensland Brain Institute, The University of Queensland. Speaking from Brisbane, Australia.
"p75 cleavage-mediated neuronal death due to sleep apnea: risk for AD"
Intermittent hypoxia but not sleep deprivation in mouse models results in the death of cholinergic basal forebrain neurons, a risk factor for Alzheimer's. The neuronal death is mediated by p75 cleavage, which has been demonstrated by a novel cleavage-resistant knockin mouse.