14th August — 13:00 UTC (check local time) 

Chloe Peach
Assistant Professor in Molecular Pharmacology, Centre of Membrane Proteins and Receptors (COMPARE). University of Nottingham. Speaking from Nottingham, UK.

Spatiotemporal dynamics of neurotrophin receptor pharmacology 

Many diseases involve dysregulated neurotrophin signalling. By exploring TRK receptor pharmacology – how they bind ligand, signal and move around cells – we study how this is modulated by their local environment, to ultimately develop better drugs. 

11th September — 15:00 UTC (check local time) 

Jonathon Sewell
Graduate student in Chris Deppmann's and Bettina Winckler's labs at the University of Virginia, USA. Speaking from Charlottesville, VI, USA.

Making connections: NGF-regulated EVs in neural circuit formation?

Target-derived NGF dictates sympathetic circuit refinement, but its upstream effects are indirect via unknown factor(s). Other neurotrophins provide an incomplete explanation. We propose NGF-regulated extracellular vesicles may complete the story.